https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4417 Wed 11 Apr 2018 14:18:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15338 Wed 11 Apr 2018 11:45:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29901 Wolbachia. We analysed the effects of Wolbachia on dengue transmission dynamics in the presence of two serotypes of dengue using a mathematical model, allowing for differences in the epidemiological characteristics of the serotypes. We found that Wolbachia has a greater effect on secondary infections than on primary infections across a range of epidemiological characteristics. If one serotype is more transmissible than the other, it will dominate primary infections and Wolbachia will be less effective at reducing secondary infections of either serotype. Differences in the antibody-dependent enhancement of the two serotypes have considerably less effect on the benefits of Wolbachia than differences in transmission probability. Even if the antibody-dependent enhancement rate is high, Wolbachia is still effective in reducing dengue. Our findings suggest that Wolbachia will be effective in the presence of more than one serotype of dengue; however, a better understanding of serotype-specific differences in transmission probability may be needed to optimize delivery of a Wolbachia intervention.]]> Thu 17 Mar 2022 14:37:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24796 Sat 24 Mar 2018 07:14:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42270 Fri 19 Aug 2022 14:37:18 AEST ]]>